Project Scientist, Translational Drug Development and Biomarker Discovery
The University of California, Los Angeles
About this position
Position Overview
Salary range: See Table 37B for the salary range for this position. A reasonable estimate for this position is $76,700- $124,700.
Application Window
Open date: January 15, 2026 Most recent review date:Monday, Feb 16, 2026 at 11:59pm (Pacific Time) Applications received after this date will be reviewed by the search committee if the position has not yet been filled. Final date: Thursday, Apr 30, 2026 at 11:59pm (Pacific Time) Applications will continue to be accepted until this date, but those received after the review date will only be considered if the position has not yet been filled.
Position Description
The Nathanson Laboratory in the Department of Molecular and Medical Pharmacology at the University of California, Los Angeles (UCLA) seeks a Project Scientist to lead translational drug development and biomarker discovery efforts focused on glioblastoma. This position will direct clinically inspired research programs leveraging a large, well-annotated library of patient-derived cancer models to evaluate novel therapeutics, drug combinations and develop biomarkers. The Project Scientist will provide scientific leadership for multidisciplinary research teams and play a central role in integrating molecular, functional, and bioinformatic data to advance precision oncology strategies. This work is conducted in close collaboration with clinicians, computational scientists, and industry partners. The ideal candidate should have a Ph.D. in the biosciences (e.g., cancer biology, pharmacology, molecular biology, or related field). Responsibilities: • Lead translational drug development studies using patient-derived in vitro and in vivo cancer models, including orthotopic xenograft systems. • Design and execute clinically relevant experimental paradigms that model therapeutic response, adaptation, and resistance. • Direct biomarker discovery and validation efforts, integrating multi-omic, functional, and phenotypic datasets. • Oversee analysis and interpretation of large-scale bioinformatic datasets in collaboration with computational researchers. • Investigate cell fate and cell death pathways as determinants of therapeutic sensitivity and resistance. • Manage research personnel, including trainees and technical staff. • Contribute to high-impact publications, grant applications, and intellectual property development. Previous experience with the following is highly desirable: • Biomarker discovery and integration across diverse data types. • Hands-on experience with patient-derived cancer models, including orthotopic in vivo systems. • Proficiency in handling and interpreting large bioinformatic datasets. • Strong background in cell fate pathways and mechanisms of cancer resistance. • Proven ability to lead research teams and manage complex, multi-project workflows. • Record of high-impact publications in translational oncology. • Experience designing studies that inform clinical trial strategy. • Prior participation in grant-funded, multidisciplinary research programs.
Qualifications
Basic qualificationsPh.D. in Biosciences Preferred qualificationsPrevious experience with the following is highly desirable: • Biomarker discovery and integration across diverse data types. • Hands-on experience with patient-derived cancer models, including orthotopic in vivo systems. • Proficiency in handling and interpreting large bioinformatic datasets. • Strong background in cell fate pathways and mechanisms of cancer resistance. • Proven ability to lead research teams and manage complex, multi-project workflows. • Record of high-impact publications in translational oncology. • Experience designing studies that inform clinical trial strategy. • Prior participation in grant-funded, multidisciplinary research programs.
Application Requirements
Document requirementsCurriculum Vitae - Your most recently updated C.V. Cover Letter (Optional) Statement of Research Interests and Leadership Experience Statement of Teaching (Optional) Reference check authorization release form - Complete and upload the reference check authorization release form Reference requirements 2-4 required (contact information only) References may be contacted to verify experience. Apply link:https://recruit.apo.ucla.edu/JPF10794 Help contact:bomote@mednet.ucla.edu
Job Location
Los Angeles, CA Apply now to Project Scientist, Translational Drug Development and Biomarker Discovery or Log in to your portfolio Need help? Contact the hiring department. The University of California, Los Angeles is an Equal Opportunity/Affirmative Action Employer. You have the right to an equal employment opportunity. The University of California, Los Angeles is committed to providing reasonable accommodations to applicants with disabilities. See our Jeanne Clery Disclosure of Campus Security Policy and Campus Crime Statistics Act Annual Security Reports Academic RECRUIT Personnel System University of California, Los Angeles Accessibility About California Consumer Privacy Act (CCPA) Opt-Out IconPrivacy Policy © 2007-2026 The Regents of the University of California. All rights reserved.